Now Available: HiFi Whole Genome Sequencing with Long Reads

August 16, 2023

CeGaT Research & Pharma Solutions continuously monitors technical developments and now offers long-read HiFi Whole Genome Sequencing using the PacBio Sequel® IIe platform. This new product meets the needs of scientists searching for highly accurate and comprehensive genetic information.

HiFi Whole Genome Sequencing (WGS) takes over where short read sequencing reaches its limitations. It helps researchers uncover complex genetic regions that were previously hard to analyze with short-read sequencing methods, such as repeat-rich regions or structural variations. We use PacBio’s HiFi long-read sequencing technology, which provides HiFi reads with 99.9% accuracy.

Unraveling the genome by generating HiFi reads

Long reads improve our understanding of complex genomes. The genomes of many living beings, particularly primates and humans, contain long, repetitive segments. Conventional short-read sequencing often requires computational approaches for genome assembly and variant detection, during which accuracy can decrease. Technologies known as third-generation sequencing can offer a solution: Longer read segments can provide a more accurate assembly of the genetic puzzle.

We perform third-generation sequencing using our PacBio platform. This platform generates HiFi reads up to 18kb in length to help us gain an accurate picture of the genetic information. That makes our HiFi Whole Genome Sequencing product a powerful tool for deeper insights into the genetic makeup.

If you are interested in our HiFi WGS product, feel free to get in touch with us. Our team is ready to guide you in selecting the optimal sequencing options for your project. Contact us at to learn how we can help you realize your project.