New Service: Single-Cell Immune Profiling for an In-Depth Understanding of the Immune System

May 04, 2023

CeGaT’s Research and Pharma Solutions business unit has launched Single-Cell Immune Profiling, a new product to study the immune system on single-cell resolution. By providing detailed insights into the repertoire of T-cell and B-cell receptors, Single-Cell Immune Profiling helps researchers to better understand the immune system’s response to various conditions.

Enjoy watching our contribution to “May the 4th” here:

The immune system is a complex network that plays a vital role in maintaining our health by recognizing and responding to various pathogens and foreign substances. Understanding the immune system is of utmost importance: The gained knowledge is used, for example, to develop and test targeted therapies and vaccines. The T- and B-cells, with their corresponding T-cell receptors and B-cell receptors (TCRs and BCRs, respectively), are two important components of the immune system.

Investigating the diversity of TCR and BCR repertoires through our Single-Cell Immune Profiling service provides valuable insights into the functioning of the immune system. It has a wide range of applications, including:

  • Exploring the diversity of immune cells with high accuracy and reliability
  • Investigating the response of immune cells to various diseases and therapeutic interventions
  • Developing targeted therapies and vaccines
  • Researching autoimmune diseases
  • Identifying different clonotypes and clone-specific gene expression

Exploring the immune cell diversity with high accuracy and reliability

Our Single-Cell Immune Profiling product provides a comprehensive and high-quality solution for investigating the diversity of immune cells in your samples by analyzing T-cells and B-cells at single-cell resolution. At CeGaT, we use the 10x Genomics® Chromium™ System and the latest NGS technology to provide paired-end sequences of the immune-specific regions of α- and β-chains for TCR analysis and Ig-chains for BCR analysis.

Our highly experienced team is happy to discuss with you the most appropriate sequencing approach for your project. All along you will have a single point of contact. In addition, our service can be supplemented with detailed bioinformatics analyses of your data. A project report with information on sample quality, sequencing parameters, bioinformatics analysis, and results is provided at the end of the project.

Benefit from our dedicated support and accredited workflows. Contact us today to learn more about our Single-Cell Immune Profiling product and how it can enhance your research.