Read our latest application note and learn more about the technical background of our RNA-based fusion detection.
Sensitive detection of fusion transcripts is highly relevant in tumor diagnostics, with implications for therapy and prognosis. Targeted enrichment of RNA is a comprehensive and sensitive method for this task. The Twist Target Enrichment technology is a robust workflow that allows us to integrate RNA fusion detection into automated laboratory processes and sequence samples alongside exomes without the need for a different library preparation process or separate sequencing runs. Together with our automated data analysis, we can accurately analyze patient samples to detect more than 80 therapeutically actionable fusion variants in a high-throughput manner, allowing us to report clinically actionable results and support treatment decisions.
Do you have further questions about the technologies and processes underlying our genetic diagnostics? Feel free to contact us at diagnostic-support@cegat.com.